In simplex mode, the sender is able to send data but cannot receive data, making it a mono-directional connection.

Advantages
| Advantage | Description |
|---|---|
| Simplicity | Data flowing only one way is far more simple than multidirectional |
| Cost-Effective | If data only needs to go one way, hardware can be simplified |
| No Collision | There is no risk of collision on a simplex route as it only travels one way |
| Efficient for some applications | Some setups (i.e. transporting keyboard input) only require single directional communication |
Disadvantages
| Advantage | Description |
|---|---|
| Lack of bidirectional communication | Some applications are not possible (i.e. video calls) |
| Inefficient at complex tasks | Unable to receive acknowledgements in return hence error checking is impossible |